The "Sprite Challenge" is when you chug an entire bottle or can of Sprite without burping. A girl is doing the challenge with a guy, and it's not going well for her.
After several chugs she's in pain, and thinks she's going to puke. Meanwhile, the guy takes his time, finishes, and tosses the empty bottle. But when she lets out a big burp, she loses but then "wins" because he stands up and projectile vomits all over the floor.